Tuesday, March 17, 2009

CHLOROMYCETIN* EYE OINTMENT


















Brand Name: CHLOROMYCETIN* EYE OINTMENT

Generic Name (chloramphenicol 10 mg per g)

The active component of CHLOROMYCETIN eye ointment is chloramphenicol.
Chloromycetin is indicated in the treatment of superficial ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol-susceptible organisms. Bacteriological studies should be performed to
determine the causative organisms and their sensitivity to chloramphenicol.



Brand Name: CHLOROMYCETIN* EYE OINTMENT
Generic Name (chloramphenicol 10 mg per g)
The active component of CHLOROMYCETIN eye ointment is chloramphenicol.

PHARMACOLOGICAL ACTION:
Chloramphenicol, a broad spectrum antibiotic originally isolated from Streptomyces venezuelae, is primarily bacteriostatic and acts by inhibition of protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes. Chloramphenicol is absorbed systemically from the eye, and toxicity has been reported following chronic exposure.

INDICATIONS:
Chloromycetin is indicated in the treatment of superficial ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol-susceptible organisms. Bacteriological studies should be performed to determine the causative organisms and their sensitivity to chloramphenicol.

CONTRA-INDICATIONS:
These products are contra-indicated in persons sensitive to any of their components.
The use of chloramphenicol during pregnancy is best avoided. Chloramphenicol is excreted in breast milk; use is not recommended during lactation because of the possibility of adverse effects on the nursing infant.

WARNINGS:
Blood dyscrasias, including aplastic anaemia, may be associated with the use of chloramphenicol. Adequate blood tests should be carried out during prolonged or intermittent therapy.
Bone marrow hypoplasia following the prolonged topical use of chloramphenicol eye drops has been reported.
Chloromycetin is considered unsafe in patients with acute porphyria.
Ophthalmic ointments may retard corneal wound healing.

DOSAGE AND DIRECTIONS FOR USE:
Chloromycetin Redidrops 0,5%: Instil 2-3 drops in the eye every 2-3 hours. Discard 30 days after opening.
Chloromycetin Ophthalmic Ointment 1%: A small amount of ointment is placed in the eye every three hours.
N.B. With both these preparations, administration should be continued day and night for the first 48 hours after which the interval between applications may be increased. Treatment should be continued for at least 48 hours after the eye appears normal.

SIDE EFFECTS AND SPECIAL PRECAUTIONS:
The prolonged use of antibiotics may occasionally result in overgrowth of non-susceptible organisms, including fungi. If new infections appear during medication, the drug should be discontinued and appropriate measures should be taken.
In all except very superficial infections, the topical use of Chloramphenicol should be supplemented by appropriate systemic medication.
Signs of local irritation with subjective symptoms of itching or burning, angioneurotic oedema, urticaria, vesicular and maculopapular dermatitis have been reported in patients sensitive to chloramphenicol and are causes for discontinuing the medication. Similar sensitivity reactions to other materials in topical preparations may also occur.
If irritation, pain, swelling, lacrimation, or photophobia occur after undesired eye contact, the exposed eye(s) should be washed out with water for at least 15 minutes. If symptoms persist, a doctor should be consulted.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
See "Side-Effects and Special Precautions".
Treatment: Symptomatic and supportive.

IDENTIFICATION:
(1) Chloromycetin Redidrops 0,5%: A bright, colourless to faint yellow, aqueous solution, practically clear and practically free from particles.
(2) Chloromycetin Ophthalmic
Ointment 1%: A smooth, uniform, translucent, greasy ointment.

PRESENTATION:
Chloromycetin Redidrops 0,5%: Plastic bottle containing 10 mL solution.
Chloromycetin Ophthalmic Ointment 1%: Tubes of 3,5 g.

STORAGE INSTRUCTIONS:
Chloromycetin Redidrops 0,5%: Store between 2° and 8°C.
Chloromycetin Ophthalmic Ointment 1%: Store in a cool place (below 25°C).
KEEP OUT OF REACH OF CHILDREN.

Cheap Online Chloromycetin


Brand name: Chloromycetin
Generic name: Chloramphenicol
Chloromycetin (Chloramphenicol) is an antibiotic used to treat eye infections.





Brand name: Chloromycetin
Generic name: Chloramphenicol

Common uses

This medicine is an antibiotic used to treat eye infections.

Before using


Warning: very rarely, serious, even fatal, blood disorders (e.g., bone marrow hypoplasia, aplastic anemia) have occurred while using this medicine. Do not use Chloromycetin if safer, effective medicines can be used. Immediately notify your doctor if you have easy bruising or bleeding, persistent sore throat, fever, or unusual fatigue. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking. Inform your doctor of any other medical conditions or allergies.

Directions

Follow the directions for using this medicine provided by your doctor. To use this medicine, first, wash your hands. Tilt your head back and, with your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Do not blink and keep your eyes closed for 1 or 2 minutes. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from entering your medicine, do not touch the applicator tip to any surface including your eye. Wipe it with a clean tissue. Keep the container tightly closed.

Store this medicine as directed on the prescription label. To clear up your infection completely, continue using this medicine for the full course of treatment even if your symptoms disappear in a few days. Do not miss any doses. If you miss a dose of this medicine, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Cautions

If your symptoms do not improve within a few days or if they become worse, check with your doctor. It is usually recommended that you do not wear contact lenses while using this medicine. Check with your doctor before wearing them. Sterilize contact lenses according to manufacturer's directions.

Possible side effects

A side effect, that may go away during treatment, is stinging upon application. If it continues or is bothersome, check with your doctor. Check with your doctor as soon as possible if you experience redness, irritation, swelling, or continued stinging. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

If you take too much

If overdose is suspected, contact your local poison control center or emergency room immediately. This medicine may be harmful if swallowed.

Additional information

Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children.

Drug interactions

Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Some medicines or medical conditions may interact with this medicine. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking.